胡驰
学术博士生导师
职称:副教授
***
学院:工学院
chihu@cpu.edu.cn
招生学科:制药工程学
个人简介

胡驰,副教授,博士生导师。2016年入职中国药科大学,入选江苏省“双创博士”和“333工程”人才计划。研究方向整合核酸适配体、纳米材料、近红外荧光探针等技术,开发基于纳微体系的生物过程强化新方法与新工艺,主要包括:(1)以微流控/3D打印为加工平台制备全细胞微球载体,强化生物催化过程;(2)基于葫芦脲大环分子的主客体识别,对不可成药靶点进行原位分析和活体成像,筛选先导化合物并进行药理机制研究。

代表性论文:

1. Zhihang Zhu, Lancheng Wang, Yan Jia, Shiqi Duan, Siyu Li, Le Jiang, Xiaoxuan Lin, Fang Yan, Chenzhi Hou,* Chi Hu,* and Bin Di. Magnetic Liposomes Infused with GPCR-Expressing Cell Membrane for Targeted Extraction Using Minimum Organic Solvent: An Investigative Study of Trace THC in Sewage. Anal. Chem. 2023, 95, 34, 12613-12622. (IF=7.4)

2. Yan Jia,1 Lili Xu,1 Lancheng Wang, Kun Yan, Jieru Chen, Pengcheng Xu, Bin Di,* Fang Yan,* Chi Hu.* A light-up fluorescence probe for wash-free analysis of Mu-opioid receptor and ligand-binding events. Analytica Chimica Acta 2023, 1261, 341220. (IF=6.2)

3. Chenzhi Hou, Yuling Zhong, Lan Zhang, Muyuan Liu, Fang Yan, Mengyi Chen, Youmei Wang, Peng Xu, Mengxiang Su, Chi Hu*, Bin Di*. Estimating the prevalence of hypertension in 164 cities in China by wastewater-based epidemiology. Journal of Hazardous Materials 2023, 443, 130147. (IF=13.6)

4. Kun Yan, Lancheng Wang, Zhihang Zhu, Shiqi Duan, Zhendong Hua, Peng Xu, Hui Xu, Chi Hu*, Youmei Wang*, Bin Di*. Cucurbituril-protected dual-readout gold nanoclusters for sensitive fentanyl detection. Analyst 2023, 148, 1253-1258. (IF=4.2)

5. Lancheng Wang, Mingjie Xu, Huimin Zhou, Kun Yan, Shiqi Duan, Dandan Xue, Youmei Wang*, Bin Di*, Chi Hu*. Teaching PCR for simultaneous sensing of gene transcription and downstream metabolites by cucurbit[8]uril-mediated intervention of polymerase activity. Analytical Chemistry 2022, 94(24), 8715-8723. (IF=8.0)

6. Huimin Zhou, Huilin Wen, Lancheng Wang, Mingjie Xu, Yan Jia, Shiqi Duan, Bin Di, Ziyi Yu*, Chi Hu*. Label-free tumor cell screening based on IDO1-mediated tryptophan metabolism at single cell level. Analytical Biochemistry 2022, 659, 114936. (IF=3.1)

7. Shiqi Duan, Yan Jia, Zhihang Zhu, Lancheng Wang, Peng Xu, Youmei Wang, Bin Di*, Chi Hu*. Induction of CYP450 by illicit drugs: Studies using an in vitro 3D spheroidal model in comparison to animals. Toxicology Letters 2022, 367, 88-95. (IF=4.2)

8. Kun Yan, Lancheng Wang, Huimin Zhou, Zhendong Hua, Peng Xu, Hui Xu, Youmei Wang*, Bin Di*, Chi Hu*. Cucurbituril-mediated AIE: An unconventional indicator displacement assay for ketamine detection. Dyes and Pigments 2022, 197, 109875. (IF=5.1)

9. Sibo Zhao, Huilin Wen, Yangteng Ou, Minhui Li, Lancheng Wang, Huimin Zhou, Bin Di, Ziyi Yu,* Chi Hu*. A new design for living cell-based biosensors: microgels with a selectively permeable shell that can harbor bacterial species. Sensors and Actuators B: Chemical 2021, 334, 129648. (IF=7.1)

10. Shujie Cheng, Haowen Shen, Sibo Zhao, Yuanxin Zhang, Hui Xu, Lancheng Wang, Bin Di,* Lili Xu,* and Chi Hu*. Orally administered mesoporous silica capped with the cucurbit[8]uril complex to combat colitis and improve intestinal homeostasis by targeting the gut microbiota. Nanoscale 2020, 12, 15348-15363. (IF=6.8)

11. Li-li Xu1, Cui-cui Li1, Lu-yan An, Zhen Dai, Xiao-yi Chen, Qi-dong You,* Chi Hu,* Bin Di*. Selective apoptosis-inducing activity of synthetic hydrocarbon-stapled SOS1 helix with d-amino acids in H358 cancer cells expressing KRASG12C. European Journal of Medicinal Chemistry 2020, 185, 111844. (IF=6.7)

12. Jing Jia, Huilin Wen, Sibo Zhao, Lancheng Wang, Haishi Qiao, Haowen Shen, Ziyi Yu, Bin Di*, Lili Xu*, and Chi Hu*. Displacement Induced Off-On Fluorescent Biosensor Targeting IDO1 Activity in Live Cells. Analytical Chemistry 2019, 91, 14943-14950. (IF=6.3)




 

个人经历
科研项目
科研专利
发表论文
获奖成果
教材专著

研究方向

基于纳微体系的生物过程强化新方法与新工艺