周磊，女，博士，副教授，博士研究生导师。2012年本科毕业于湖南师范大学生物科学基地班，随后保送至复旦大学化学系攻读博士学位。曾先后在德州农工大学和亚利桑那州立大学从事博士后工作。2022年加入中国药科大学，主要研究领域为近红外荧光探针的合成与生物多重检测。迄今共发表SCI论文和专著20余篇，其中以第一作者或通讯作者身份在Nature Communications, J. Am. Chem. Soc., Angew. Chem. Int. Ed., Analytical Chemistry等国际一流期刊发表研究论文7篇，论文总引用次数超高3000次。

研究方向

1. 稀土上转换荧光探针的发光性能与结构调控及生物应用

2. 荧光成像在肿瘤等重大疾病相关蛋白质和核酸的诊断与潜在致病机理的研究

3. 基于荧光原位杂交的空间转录组学

招生专业： 100704  药物分析学

     070300  化学    

联系方式：leizhou@cpu.edu.cn

办公地址：实验楼B307

部分代表性论文

1. Yang, Y.,Wang, R.*, Jin, X., Zhong, W.*, Zhou, L.* Quantitative Near-Infrared Photoacoustic Imaging of Gamma-Glutamyl Transpeptidase Activity in Tumors. Anal. Chem. 2025, 97, 24, 12540-12547. (IF=6.785)

2. Wang, R.⁺, Zhou, L.⁺, Yang, Y., Zhao, F., Zhao, Sun,X., Liu, X., Zou, Z. Liang, G. Spatially Quantitative Imaging of Enzyme Activity in a Living Cell. J. Am. Chem. Soc. 2024, 146(50), 34870-34877. （共同一作）(IF=14.612)

3. Zhang, P.+, Zhou, L.+, Wang, R., Zhou, X., Wan, Z., Wang, S.* Evanescent Scattering Imaging of Single Protein Binding Kinetics and DNA Conformation Changes. Nat. Commun., 2022, 13, 2298.（共同一作）(IF=12.121)

4. Zhou, L., Kurouski D.* Structural Characterization of Individual α-Synuclein Oligomers Formed at Different Stages of Protein Aggregation by Atomic Force Microscopy-Infrared Spectroscopy. Anal. Chem., 2020, 92, 10, 6806. (IF=6.785)

5. Zhou, L., Fan, Y., Wang, R., Li, X., Fan, L. and Zhang, F.* High-capacity upconversion wavelength and lifetime binary encoding for multiplexed biodetection. Angew. Chem. Int. Ed., 2018, 57, 12824. (IF=12.959)

4. Zhou, L., Wang, R., Yao, C., Li, X., Wang, C., Zhang, X., Xu, C., Zeng, A., Zhao, D., Zhang, F.* Single-band upconversion nanoprobes for multiplexed simultaneous in situ molecular mapping of cancer biomarkers. Nat. Commun., 2015, 6: 6938. (IF=12.121)

6. Zheng, Y., Ma, X., Zhou, S., Lei, W., Luo, X., Zhou, L.*, Xu, K., Zhong, W.* Alkaline Phosphatase and ATG4B Sequentially-Activated Fluorescence Probe for Cancer Cell-Specific Live Imaging of Autophagy. Anal. Chem. 2025, 97, 15, 8370-8377. (IF=6.785)

7. Li, X., Zhou, L., Wei, Y., El-Toni, A.M., Zhang, F.*, Zhao, D.* Anisotropic growth-induced synthesis of dual-compartment Janus mesoporous silica nanoparticles for bimodal triggered drugs delivery. J. Am. Chem. Soc., 2014, 136, 15086. (IF=14.612)

8. Li, X., Zhou, L., Wei, Y., El-Toni, A.M., Zhang, F.*, Zhao, D.* Anisotropic encapsulation-induced synthesis of asymmetric single-hole mesoporous nanocages. J. Am. Chem. Soc., 2015, 137, 5903. (IF=14.612)