窦晓巍
学术博士生导师
职称:教授
***
学院:理学院
cpudxw@126.com
招生学科:化学,药学-药物合成与工艺优化
个人简介

窦晓巍,教授,博士研究生导师,理学院化学实验中心主任。江苏省优青(2020),江苏省六大人才高峰(2017),江苏省双创博士(2017)。

2009年毕业于南京大学化学化工学院基地班,2013年博士毕业于新加坡国立大学化学系,获国家优秀留学生奖。作为项目负责人主持国家自然科学基金,江苏省自然科学基金,中国药科大学高层次人才科研启动经费等项目。已在J. Am. Chem. Soc.Angew. Chem. Int. Ed.Nat. Commun.ACS Catal.Chem. Sci.Green Chem.Org. Lett.等国际知名刊物上发表研究论文四十余篇,多篇论文被SYNFACTS等专业评述性杂志收录并被亮点介绍。申请发明专利多项,授权发明专利7项,部分成果实现转化和商品化。受邀担任Nat. Commun.Angew. Chem. Int. Ed.Adv. Sci.ACS Catal.等近二十种学术期刊的审稿人。


近年代表性论文:

(1)Yang, Y.;+ Wu, C.;+ Xing, J.; Dou, X.* 'Developing biarylhemiboronic esters for biaryl atropisomer synthesis via dynamic kinetic atroposelective Suzuki-Miyaura cross-coupling' J. Am. Chem. Soc. 2024, 146, 6283-6293. (IF = 15)

(2)Yin, L.;+ Li, J.;+ Wu, C.;+ Zhang, H.; Zhao, W.; Fan, Z.; Liu, M.; Zhang, S.; Guo, M.;* Dou, X.*; Guo, D.* 'Asymmetric synthesis of P-stereogenic phosphindane oxides via kinetic resolution and their biological activity' Nat. Commun. 2024, 15, 2548. (IF = 16.6)

(3)Zhou, Q.;+ Meng, R.;+ Xing, J.;* Yao, W.; Dou, X.* 'Rhodium-catalyzed chemodivergent synthesis of organosilicons enabled by controllable C–Si bond activation' ACS Catal. 2023, 13, 8516-8524. (IF = 12.9)

(4)Wu, C.; Chang, Z.; Peng, C.; Bai, C.; Xing, J.; Dou, X.'Catalytic asymmetric indolization by a desymmetrizing [3+2] annulation strategyChem. Sci. 2023, 14, 7980-7987. (IF = 8.4)

(5)Ye, B.; Yao, J.; Wu, C.; Zhu, H.; Yao, W.; Jin, L.; Dou, X.* 'Rhodium-catalyzed asymmetric conjugate pyridylation with pyridylboronic acids, ACS Catal. 2022, 12, 2434-2440. (IF = 13.7)

(6) Liu, N.;+ Zhu, W.;+ Yao, J.; Yin, L.; Lu, T.; Dou, X.* 'Catalyst-controlled chemodivergent synthesis of spirochromans from diarylideneacetones and organoboronic acids' ACS Catal. 2020, 10, 2596-2602. (IF = 13.1)

(7) Xing, J.; Zhu, W.; Ye, B.; Lu, T.; Hayashi, T.;* Dou, X.* 'Rhodium-catalyzed diverse arylation of 2,5-dihydrofuran: controllable divergent synthesis via four pathways' ACS Catal. 2020, 10, 2958-2963. (IF = 13.1) 

(8) Yin, L.;+ Xing, J.;+ Wang, Y.; Shen, Y.; Lu, T.;* Hayashi, T.;* Dou, X.* 'Enantioselective synthesis of 3,3’-diaryl-SPINOLs: Rh-catalyzed asymmetric arylation/BF3-promoted spirocyclization sequence' Angew. Chem. Int. Ed. 2019, 58, 2474-2478. (IF = 12.96)

(9) Yao, J.; Liu, N.; Yin, L.; Xing, J.; Lu, T.; Dou, X.* 'Catalytic asymmetric synthesis of chiral phenols in ethanol with recyclable rhodium catalystGreen Chem. 201921, 4946-4950. (IF = 9.48)

(10) Liu, N.; Yao, J.; Yin, L.; Lu, T.; Tian, Z.;* Dou, X.* 'Rhodium-catalyzed expeditious synthesis of indenes from propargyl alcohols and organoboronic acids by selective 1,4-rhodium migration over β-oxygen elimination' ACS Catal. 20199, 6857-6863. (IF = 12.35)





 

个人经历
科研项目
科研专利
发表论文
获奖成果
教材专著

研究方向

不对称合成;药物合成工艺及药物杂质研究;小分子药物开发