陈美容，博士，药学院药理系副教授，硕士生导师。

2016年博士毕业于北海道大学生命科学学院，先后在北海道大学、斯克里普斯研究所从事博士后研究，2021年加入中国药科大学药学院。

主要研究方向： (1)靶向核酸的细菌免疫机制及抗感染研究。(1)tRNA氨酰化及核酸修饰的分子机制研究。

以第一作者或通讯作者(含共同)在Nature Chemical Biology、Nature Communications，Nucleic Acids Research，Cell Reports等期刊发表论文。主持国家自然科学基金面上项目2项、国家自然科学基金青年项目、江苏省“双创博士”资助项目。

联系方式: chenmr@cpu.edu.cn

近五年代表论文：

1. Guo, L. ^#, Huang P. ^#, Li, Z. ^#, Shin, Y., Yan, P., Lu, M., Chen, M.*, Xiao, Y.* Auto-inhibition and activation of a short Argonaute-associated TIR-APAZ defense system. Nature Chemical Biology, 2023.

2. Yuan, C. ^#, Li, Z. ^#, Luo, X., Huang, P., Guo, L., Lu, M., Xia, J., Xiao, Y.*, Zhou, X.*, Chen, M.*, Mammalian trans-editing factor ProX is able to deacylate tRNAThr mischarged with alanine. International Journal of Biological Macromolecules, 2023.

3. Zeng, T., Yin, J., Liu, Z.W.; Li, Z., Zhang, Y., Lv, Y., Lu, M., Luo, M., Chen, M.*, Xiao, Y.* Mechanistic insights into transposon cleavage and integration by TnsB of ShCAST system. Cell Reports, 2023.

4.Yang, H., Yan, R., Li, Y., Lu, Z., Bie, X., Zhao, H., Lu, F.^*, Chen, M.*, Structure–Function Analysis of a Quinone-Dependent Dehydrogenase Capable of Deoxynivalenol Detoxification. Journal of Agricultural and Food Chemistry, 2022.

5. Niu, J., Meng, F., Zhou, Y., Zhang, C., Lu, Z., Lu, F.^*, Chen, M.*, Non-classical secretion of a type I L-asparaginase in Bacillus subtilis. International Journal of Biological Macromolecules, 2021. 

6. Chen, M., Kuhle, B.^*, Diedrich, J., Liu, Z., Moresco, J., Yates, J., Pan, T., and Yang, X.L.^*, Cross-editing by a tRNA synthetase allows vertebrates to abundantly express mischargeable tRNA without causing mistranslation. Nucleic Acids Research, 2020.

7. Chen, M.^#, Gai, Z^#, Okada, C., Ye, Y., Yu, J., and Yao, M^*, Flexible NAD⁺ Binding in deoxyhypusine synthase reflects the dynamic hypusine modification of translation factor IF5A. International Journal of Molecular Sciences, 2020. 

8. Chen, M., Kato, K., Kubo, Y., Tanaka, Y., Liu, Y., Long, F., Whitman, WB., Lill, P., Gatsogiannis, C., Raunser, S., Shimizu, N., Shinoda, A., Nakamura, A., Tanaka, I., and Yao, M.^*, Structural basis for tRNA-dependent cysteine biosynthesis. Nature Communications, 2017.

9. Chen, M., Nakazawa, Y., Kubo, Y., Asano, N., Kato, K., Tanaka, I., and Yao, M.^*, Crystallographic analysis of a subcomplex of transsulfursome with tRNA for Cys-tRNA^Cys synthesis. Acta Crystallographica Section F: Structural Biology Communications, 2016. 

10. Ye, Y.^#, Chen, M.^#, Kato, K., and Yao, M.^*, The pH-dependent conformational change of eukaryotic translation initiation factor 5: Insights into partner-binding manner, Biochemical and Biophysical Research Communications, 2019.